Heaping allergies in Childhood increase in later life, the risk for mental and chronic inflammatory diseases. This is the conclusion at the end of the University of Zurich and University of Lausanne Researchers in a new study.
they found that the expression of children’s diseases and allergies, as well as trauma in childhood is associated with later disease susceptibility.
For their study, the researchers evaluated the first author Vladeta Ajdačić-Gross from the University of Zurich to Study the epidemiological data of nearly 5000 people, the middle of the 20th century. Century were born. On the basis of the pattern of Disease in Childhood, scientists have identified five groups, such as the University of Zurich announced on Monday.
These groups are characterized on the basis of biological markers such as white blood cells and inflammation markers, it was said. Then the researchers put the disease pattern of Childhood in relationship to chronic inflammatory diseases and mental disorders in adulthood. From their results, they reported recently in the journal “BMC Medicine”.
allergies and trauma to make susceptible
A connection between the disease patterns of the Childhood and the later susceptibility to mental illness, the researchers found, therefore, in the case of three groups: an “atopic” group (7 percent), with several allergies, a “mixed” group (9 percent) with occasional allergies, and childhood diseases such as scarlet fever, whooping cough, or rubella, and a “traumatized” group, in which the people in Childhood, the great psycho-social stress experienced. The latter were more susceptible to allergies, but relatively resistant to viral diseases in children.
The same three groups were also more susceptible to chronic inflammatory diseases. In the traumatized group, this increased risk of the disease was limited only to the women, wrote the researchers in the journal article.
Once resilient, always resilient
The largest group – nearly 60 percent of the examined persons had a inconspicuous, “neutral” immune system with a relatively low burden of disease in childhood. The second largest with around 20 per cent had a particularly robust (resilient) the immune system: If you manifest symptoms of measles, Mumps, and rubella, for which there was no Vaccination were significantly less than in the “neutral” group.
The resilient group was protected according to the study, also in adult age better, both mental as well as chronic inflammatory diseases. “The results indicate that the immune system place as a switch between somatic and mental processes work,” said Ajdačić-Large in accordance with the message. “They help us to understand, which is why a lot of people without psychosocial Impacts of mental complaints are obtained and tend to be which is why, conversely, traumatized individuals with chronic inflammatory diseases.”
confirmation of the hygiene hypothesis
Further comparison analyses showed, moreover, that have shifted the proportions of the groups defined in the course of time. In older vintages, the neutral and resilient group comprises a larger proportion than in younger people. In Younger, the proportion of “atopic” group with allergies to submit.
This finding is also confirmed by the so-called “hygiene hypothesis”, which States that better Hygiene and the increased exchange of country life for the city exchange, the susceptibility to allergies in the population have increased.
The immune system in early life with less and other microbes in contact, if a child grows up in the city, as if it is, for example, on the farm large. Through contact with a variety of microbes, the immune system learns to pathogens, but the right way to deal with disease, and actually Harmless, such as Pollen. (nag/sda)
Created: 29.04.2019, 14:31 PM
