Jordnötsallergi is relatively common and can in worst case lead to a life-threatening allergic reaction. The one who is allergic to peanuts today must avoid peanuts in the rest of life.
There is a lot of research to find a way to cure jordnötsallergi of the who have already become allergic. In various studies, researchers have attempted to wean the baby gradually with very small amounts of peanuts to then increase the dose. For example, a patch which slowly releases the jordnötsprotein worked on mildly or moderately allergic children. In other studies, with the gradual habituation of the small amounts of jordnötsprotein in the food has been relatively small.
study of 551 children and adults was gradually increasing the amount of jordnötsprotein in a year published in the scientific journal the New England Journal of Medicine. The study distinguished between how the treatment worked in children between 4 to 17 years and adults between 18 and 55 years. Most in the study were small capsules with jordnötsprotein, but a quarter received a placebo. No one knew who got the jordnötsprotein and who got the idle reading.
At the end of the study was a födoämnesprovokation where those who participated in the study got to try to eat peanuts. 67.2 per cent in the group of children who received jordnötsprotein during the year was able to eat the equivalent of two peanuts without any major allergic reaction. In the group of children who received placebo, it was only four per cent as it could. Half of the children who received the active treatment were able to eat the equivalent of four peanuts. The study could not show any effect in people older than 18 years.
Before the study, reacted to the children of less than one-third of a peanut. When they had gone through the treatment could take the average of two whole peanuts. It means a lot, to reduce Cratosslot the fear of serious allergic reactions. However, the treatment had a price in the form of allergic reactions, ” says Magnus Wickman, barnallergiläkare and professor at Karolinska institutet.
got any allergic reaction during the study. 14% of children in the group that received jordnötsprotein had such a severe allergic reaction that they needed to use adrenalinpenna. Some also jumped out of the study because of side effects.
this study shows that one can treat even those who have developed jordnötsallergi, but it is not risk free and nothing to try on at home, ” says Magnus Wickman.
It was surprising with the study, according to Magnus Wickman, was that the treatment worked even on difficult jordnötsallergiska children. In this study, 72 per cent of the participants had previous anaphylaxis, a very severe allergic reaction that can be fatal.
– In previous studies have usually only included those with mild to moderate jordnötsallergi, because those with difficult allergy reacted too much on the reading. It seems that the ability to develop tolerance depends more on how long you have had a jordnötsallergi than how allergic you are, ” he says.
the major benefit of the study is that there is now a drug, with the exact amount of jordnötsprotein. It allows the methods to gradually get used allergic children can be standardized. Despite the risks, some parents think that reading is worth it.
in Order to maintain the tolerance, the kids can have to keep small amounts of peanuts on a regular basis. It is currently uncertain what the long-term effects of the treatment are. There is a smaller study where the majority of the children are still able to eat peanuts after four years, despite the fact that not all eaten small amounts on a regular basis. In the study were combined jordnötsproteinet with a special probiotics.
Read more: New strategy to reduce children’s food allergies
Many parents wonder how they can reduce the risk that the child will be allergic from the beginning. Previous studies have shown that children with high risk for developing jordnötsallergi had a greatly reduced risk if they early had to eat small amounts of peanuts every day. Some countries have already implemented recommendations to early to let the children eat the peanuts. The nfa is currently reviewing the recommendations.
– most parents can probably do as they wish, but as a doctor it is very difficult to give advice on the early habituation of the tolerance because we have too little data, ” says Magnus Wickman.
