“Jo, 71, has never known pain, anxiety or fear”
“Now, scientists have found an unknown gene in her dna that can lead to new methods for pain relief”
“To give birth to a child was that ”a tickle”.”
“To break the arm, operate your fingers crossed, or replace the hip joint didn’t feel either.”
“Well, Cameron, 71, has lived a life without pain, stress, fear or anxiety – she has just been cheerful and happy.”
“Thanks to a mutation in an unknown gene, which scientists have now discovered.”
“Sure sounds like a wonderful life.”
“albeit with some minor drawbacks.”
“But Jo Cameron, in Scotland, has lived a wonderful life.”
“Sure, she was a little bit different than the others, but she just figured it was so she was. And her parents made no big deal of it either.”
“Broke his arm – without the pain”
“when she eight-year-old broke his arm – and not said anything for several days.”
“It didn’t hurt.”
“It was when benbitarna healed up in a strange angle which the damage was discovered.”
“Or like when she would give birth to a child.”
“She was of course told by their girlfriends that it would be painful.”
“But the hours passed – but she felt nothing.”
“Someone epiduralbedövning she needed not.”
“– I felt that my body changed, but it did not hurt, ” says Jo Cameron to The New York Times, which tells her story.”
“by Yourself similar to she their children’s births at the – a ”tickle”.”
“And afterwards she said to the others who would become mothers:”
“– don’t Worry, it’s not nearly as dangerous as people say.”
“do not Know when she burns herself.”
“It would take four decades before Jo Cameron understood that she is unique – and that the other mothers had a completely different experience.”
“today is Jo Cameron retired after having worked as a teacher. She lives with her husband in Inverness in Scotland, at the fabled Loch Ness lake, where she lives a perfectly normal life, albeit perhaps a little happier and less smärtfyllt than normal.”
“Her two children, a son and a daughter, are adults.”
“She has always been busy, but never felt stressed or scared, never been depressed or had anxiety.”
“I am very happy,” she says.”
“Her good mood was just part of her personality.”
“Just as there to not feel pain.”
“at Home, she has countless times leaned with the scorching Spanking-cooker without understanding that she burned until she felt the smell.”
“the Smell of burning flesh.”
“– I’m vegan, so the smell is pretty obvious. There is no other frying of meat at once in this house, ” she says to The Guardian. “
“don’t Need painkillers.”
“When she for two years was in an auto accident and was prejad of the road. The car ended up upside down in the ditch, but she climbed just out and hurried up to the driver as prejat her to comfort and help the young man who shook off the shock.”
“That she herself was damaged, she discovered only afterwards.”
“It was, of course, not just about personality – but something completely different.”
“five years ago started the truth is revealed.”
“Then Jo Cameron in several years gone bad, to the hip, sometimes folded. But each time she sought care with her doctor or at the hospital dismissed her – she had, of course, not evil.”
“Only after three, four years was x-rayed, finally, the hip – and then it turned out that her hip was completely söndervittrad.”
“– I felt nothing. They could not understand it, ” says Jo Cameron to The Guardian.”
“Her dna provided the answer.”
“the Hip was understand out – but the day after the operation were Jon Cameron to the doctors’ amazement at the two analgesic tablets.”
“At the hospital, it was discovered also that her thumbs were severely deformed by osteoarthritis. “
“She was booked in for a dubbeloperation, which a doctor described as very painful (”excruciating”.”
“But Jo Cameron felt, as usual, almost nothing afterwards and didn’t have any painkillers.”
“– I guarantee that I don’t need anything, ” said Jo Cameron.”
“It fascinated the doctor so much that he referred her to the smärtspecialister at University College London, UCL, in London.”
“And in an article in the new issue of the medical journal British Journal of Anaesthesia reveal the researchers what they had found – in Jo Cameron’s dna.”
“Where have they namely found the explanation and the discovery makes her unique.”
“– We have never met a patient like her, ” says John Wood, who leads the research at UCL.”
“Increasing the happiness and the healing of wounds”
“In her dna found two mutations, which together dampen the pain and anxiety and instead increase happiness, forgetfulness, and wound healing.”
“The first mutation is fairly common.”
“It reduces the activity of a gene, called FAAH, in the body.”
“The gene creates an enzyme that breaks down anandamide, which has the same properties as cannabis affects both pain sensitivity, mood and memory.”
“The less anandamidet breaks down the more pain relief, happiness and oblivion.”
“The other mutation is extremely rare and baffled scientists in the beginning.”
“Well, Cameron is missing a piece of a dna string. It cut off the beginning of a gene which has so far been unknown to the researchers.”
“Now called FAAH-OUT and can best be described as a volume control to the FAAH gene.”
“The two mutations means that the analgesic anandamidet built up in Jo Cameron’s body – she had twice as much of the substance in the body that other people.”
“For Jo Cameron, was the researchers’ discovery, an aha-experience.”
“It explained much in her life.”
“Also the disadvantages, that oblivion.”
“All her life she has been looking after the keys and other things that she misplaced.”
“But mostly it’s been positive.”
“I was pretty amused when I found out,” she says to The Guardian.”
“– It is good in many ways but not in others. I do not have the same alarm as everyone else has.”
“Her mother feel the pain like all the others, henens daughter as well.”
“Her son has inherited the one, the more common mutation of the FAAH gene and has reduced sensitivity to pain.”
“Just like his mother, he never take pain killers or pain relievers.”
“Scientists believe that Jo Cameron inherited genmutationerna of his dad, who unfortunately is dead.”
“But the researchers hope that the discovery of her dna can help other people in the future, through new methods of pain relief.”
“It means hope for all those who suffer from difficulty of different pains.”
” it– It’s very much we can learn from her. Once we have understood how the new gene works, we can think about gene therapies, which mimics the effects she was experiencing, ” says James Cox, a researcher who participated in the study to The Guardian.”